Preheat your oven to 375°F (190°C).
In a large mixing bowl, combine shredded chicken, broccoli, cauliflower rice, bell peppers, garlic powder, onion powder, salt, and pepper.
Add the cream or sour cream and half of the shredded cheddar cheese to the bowl, stirring well to combine.
Pour the mixture into a greased 9x13 inch baking dish, spreading it evenly.
Sprinkle the remaining shredded cheddar cheese on top.
Bake for 25-30 minutes, or until the cheese is melted and bubbly.
Remove from the oven and let it cool for a few minutes before serving.